STUDY 001 · MUCOPOLYSACCHARIDE POLYSULFATE
Why MPS holds water — and
why the dermis notices.
Mucopolysaccharide polysulfate (MPS) is a semi-synthetic glycosaminoglycan — a long, sulphated chondroitin backbone with dense hydrogen-bonding surfaces. Applied topically, it pulls water into the outermost dermis and stimulates endogenous hyaluronate synthesis, restoring viscoelasticity to skin that has lost it.
Over five decades of clinical use, MPS creams have been documented for hydration, anti-inflammation, microcirculation and superficial thrombolysis — the pharmacological backbone of Hirudiox®.
+38%
Skin hydration Δ vs. baseline · 4 wk
1.9×
Local cutaneous blood volume
50 yr
Cumulative clinical record
>500 Da
Molecular weight, dermal-reaching
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